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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Linker of activated T cells ： ウィキペディア英語版 Linker of activated T cells The Linker for Activation of T cells, also known as LAT, is a protein which in humans is encoded by the ''LAT'' gene. Alternative splicing results in multiple transcript variants encoding different isoforms. == Function == The protein encoded by this gene is phosphorylated by ZAP70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts (also known as glycosphingolipid-enriched microdomains or GEMs) and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Linker of activated T cells」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.